Entity Address, City or Town Entity Address, City or Town Entity Ex Transition Period Entity Ex Transition Period Fair Value Disclosures [Abstract] Commitments and contingencies. Commitments And Contingencies [Line Items] Commitments And Contingencies [Line Items] Earnings Per Share [Abstract] Fair Value, Inputs, Level 1 [Member] Level 1 Manufacturing equipment Manufacturing Facility [Member] Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities: Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield Impairment charges on marketable securities related to other-than-temporary. Impairment Charges On Marketable Securities Related To Other Than Temporary Impairment charges on marketable securities related to other-than-temporary Amendment Flag Amendment Flag Property and equipment included in accounts payable and accrued and other current liabilities Capital Expenditures Incurred but Not yet Paid Stock issued during period shares stock options exercised and vesting of restricted stock units. Stock Issued During Period Shares Stock Options Exercised And Vesting of Restricted Stock Units Issuance of common stock upon exercise of stock options and vesting of restricted stock units, shares Available-for-sale marketable securities contractual maturities term. Available For Sale Marketable Securities Contractual Maturities Term Available-for-sale marketable securities contractual maturities term South San Francisco, California. 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Significant Accounting Policies [Line Items] Significant Accounting Policies [Line Items] Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Net loss before income tax expense Entity Address, State or Province Entity Address, State or Province 2027 Lessee, Operating Lease, Liability, to be Paid, Year Four Geographical [Axis] Geographical Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net change in cash, cash equivalents and restricted cash Document Type Document Type Percentage of shares of common stock outstanding on last day of immediately preceding year. Percentage Of Shares Of Common Stock Outstanding On Last Day Of Immediately Preceding Year Percentage of shares of common stock outstanding on last day of immediately preceding year Government Agencies Bonds US Government Corporations and Agencies Securities [Member] Office and laboratory space. Office And Laboratory Space [Member] Office and Laboratory Space Entity Shell Company Entity Shell Company Share-Based Payment Arrangement, Expense Stock-based compensation Total stock-based compensation Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value, Recurring and Nonrecurring [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Marketable Securities Debt Securities [Member] Security Exchange Name Security Exchange Name Class of Stock [Line Items] Class Of Stock [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Weighted-average period Offering period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Contractual term of stock option awards Commitments and Contingencies Disclosure [Abstract] Schedule of common stock reserved for issuance. Schedule Of Common Stock Reserved For Issuance Table [Text Block] Schedule of Common Stock Reserved for Issuance Operating lease cost Operating Lease, Cost Lessee, Operating Lease, Liability, Maturity [Table Text Block] Summary of Future Minimum Lease Payments Under Operating Lease Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Summary of Restricted Stock Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Summary of Stock Option Activity Gladstone. Gladstone [Member] Gladstone Recently Adopted Accounting Standards New Accounting Pronouncements, Policy [Policy Text Block] Annual license maintenance fees. 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Maximum Aggregate Offering Price Maximum aggregate offering price Share-Based Payment Arrangement [Text Block] Stock-Based Compensation University of Texas southwestern license agreement. University Of Texas Southwestern License Agreement [Member] University of Texas Southwestern License Agreement General and Administrative Expense General and administrative General and Administrative Expense, Total Organization, Consolidation and Presentation of Financial Statements [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted-Average Exercise Price Per Share, Outstanding Ending Balance Weighted-Average Exercise Price Per Share, Outstanding Beginning Balance Research and Development Expense [Member] Research and Development Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Risk-free interest rate, minimum Total lease cost Lease, Cost Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Retained Earnings [Member] Accumulated Deficit Security Deposit Security deposit Money Market Funds Money Market Funds [Member] Property, Plant and Equipment, Gross Total property and equipment Property, Plant and Equipment, Gross, Total Property, Plant and Equipment, Gross, Beginning Balance Property, Plant and Equipment, Gross, Ending Balance Additional Paid in Capital Additional paid-in capital Additional Paid in Capital, Total Additional Paid in Capital, Beginning Balance Additional Paid in Capital, Ending Balance Entity Interactive Data Current Entity Interactive Data Current Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental disclosure of non-cash investing and financing activities: Accrued compensation and related expenses. 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Participants To Purchase Common Stock Through Payroll Deduction Maximum Percentage Of Eligible Compensation Participants to purchase common stock through payroll deduction maximum percentage of eligible compensation Other Liabilities, Noncurrent Other Liabilities, Noncurrent, Total Other noncurrent liabilities Income Statement Location [Domain] Income Statement Location Unvested as of March 31, 2023 Unvested as of December 31, 2022 Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Shares, Outstanding Balance, shares Balance, shares Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Milestone and royalty payments. 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Lessee Operating Lease Liability Payments Due After Year Four Thereafter Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Vested Liabilities, Current [Abstract] Current liabilities: Maximum [Member] Maximum Proceeds from exercise of stock options and employee stock purchase plan Proceeds from Exercise of Stock Options and Employee Stock Purchase Plan Proceeds from exercise of stock options and employee stock purchase plan Net unrealized gain (loss) on marketable securities OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Summary of Stock-based Compensation Net cash provided by investing activities Net Cash Provided by (Used in) Investing Activities Furniture and Fixtures [Member] Furniture and Fixtures Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Issuance of common stock upon exercise of stock options, shares Shares, Options exercised Use of Estimates, Policy [Policy Text Block] Use of Estimates Stock Issued During Period, Value, Stock Options Exercised Issuance of common stock upon exercise of stock options Long-term investments in marketable securities Long-Term Investments Long-Term Investments, Total Milestone payments contingent upon achieving specific development and commercialization milestone events. 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